Availability: In Stock
Cat No.: 1185887-21-1
Biological Description:AB-FUBINACAis an indazole-based synthetic cannabinoid (CB) with 10-fold greater affinity for the central CB1 receptor (Ki = 0.9 nM) than that of JWH 018AB-FUBINACA was first synthesized by Pfizer, Inc. as a potent CB1 receptor modulator for potential therapeutic use, but recently was identified along with AB-PINACA in illegal herbal products.1,2 AB-CHMINACA is structurally related to AB-FUBINACA with a cyclohexyl group substituted for the 4-fluorophenyl group. The physiological and toxicological properties of this compound have not been determined. This product is intended for research and forensic applications.
Purity: ≥98%
Molecular formula: C
20H
28N
4O
2Molecular Weight: 129.15
Storage Instructions: Two years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
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Affix Scientific633克朗
CAS号:286370-15-8
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1克$ 1650
价格: $ 1650.00
数量:
1
库存:有存货
目录号 286370-15-8
生物学描述:
KRN633是一种有效的选择性VEGFR抑制剂。抑制人脐静脉内皮细胞中VEGFR-2的酪氨酸磷酸化(IC50 = 1.16 nmol / L)。用重组酪氨酸激酶进行的选择性分析表明,KRN633对VEGFR-1,-2和-3具有高度选择性。在无胸腺小鼠和大鼠中,KRN633在几种具有不同组织起源的体内肿瘤异种移植模型(包括肺,结肠和前列腺)中抑制肿瘤生长。KRN633还可以使一些公认的肿瘤以及那些在停止治疗后已长出的肿瘤消退。KRN633具有良好的耐受性,对动物的体重或总体健康没有明显影响。KRN633可用于治疗实体瘤和其他依赖病理性血管生成的疾病。
纯度: > 98.00%
分子式: C 2 0 H 2 1 ClN 4 O 4
分子量: 446.90
储存说明:两年-20°C粉末,2周DMSO中4°C,DMSO中6个月-80°C